The Science of Aging in a 250-Year Lifespan Era

Life sciences PhD Motoshi Hayano defines aging as a “treatable disease” and discusses AI-accelerated rejuvenation research and how a 150–250-year lifespan would reshape the way we live.

• Bryan Johnson spends ¥300M per year on longevity and has achieved a skin age of 28 and cardiopulmonary age of 18 at a chronological age of 47
• Hayano’s mentor David Sinclair treats aging as a “treatable disease” and is currently focused on neural rejuvenation
• Essential amino acids including leucine (found in BCAAs) have been found to accelerate aging — heavy protein supplementation may shorten lifespan
• Hayano’s view: bodybuilders’ excessive amino acid intake is likely linked to shorter lives
• DeepMind’s Demis Hassabis has said “almost all diseases will disappear”; AI has dramatically accelerated research over the past year
• Japan’s bioventure investment lags the US by roughly two cycles; genome-editing clinics are furthest ahead in the Middle East
• Humans are biologically designed to die at 38 but medicine has forcibly extended that — a 150–250-year lifespan era would fundamentally reshape views on marriage and childbearing
• Genome editing leaves no visible trace, raising the possibility that world leaders are quietly undergoing it

2026-04-23 · Watch on YouTube

Japanese page: 寿命250歳時代の老化科学