Weekly Dose of Optimism #183

· systems · Source ↗

TLDR

  • A curated roundup covering a16z’s AD Summit, Pi memory, Evo 2, injectable livers, Ginkgo’s Cloud Lab, and five fundraising stories.

Key Takeaways

  • a16z held an AD Summit, signaling continued institutional focus on AI and deep tech investment themes.
  • Pi memory and Evo 2 are featured as notable technical developments worth tracking for builders in compute and biology.
  • Injectable liver technology appears as a biotech highlight, pointing to progress in organ repair or regenerative medicine.
  • Ginkgo Bioworks’ Cloud Lab is included, suggesting advances in automated or remote biological experimentation infrastructure.
  • Five fundraising stories are covered alongside a sci-fi series recommendation, rounding out the weekly optimism format.

Why It Matters

  • The issue clusters compute (Pi memory), biotech (Evo 2, injectable livers), and lab automation (Ginkgo Cloud Lab), reflecting where capital and research are converging.
  • Five fundraising stories in one issue suggests continued deal flow across deep tech categories despite broader market uncertainty.
  • Not Boring’s optimism framing selects for progress signals, making it a useful filter for founders tracking what institutional observers are emphasizing.

· 2026-03-06 · Read the original